Investigator II

The FDA requires a Bioinformatician to address rapidly changing program needs across new and ongoing research projects within the Division of Applied Regulatory Science (DARS).

Essential Duties

Participate in continuous quality improvement of bioinformatic and statistical processes and will work collaboratively with other lab staffs to implement changes and training. Analysis and interpretation of high-throughput genomic, transcriptomic and/or proteomic data. Work with the laboratory lead to design, develop and validate robust workflows, as well as custom scripts, to support the analysis of high-throughput data.

Work with the laboratory lead to develop network/systems biology approaches, including analysis of regulatory networks, integrative analysis to combine evidence from multiple data modalities. Work with laboratory lead to interpret omics data and communicate results. Mining proprietary and publicly available biological data to generate novel hypotheses or insights.

Present analysis results, in a clear and concise manner, to scientific audiences. Prepare scientific manuscripts and presentations. Preferred expertise includes some or all the following: Knowledge and experience in PCR- and array-based technology, and NGS. Genomic, methylomic, transcriptomic, and/or proteomic analyses.

Omics data processing and analysis of next generation sequencing (NGS) datasets Statistical modeling Multi-omics data integration Development and implementation of complex workflows in an HPC environment.

Requirements

PhD in Molecular Biology, bioinformatics, biostatistics, or related field. Strong technical, scientific, and analytical knowledge of molecular biology methods including RT-PCR/PCR and/or DNA/RNA sequencing. More than 5 years technical experience in research laboratories/environment. Ability to evaluate data from experiments, troubleshoot, optimize, and validate experiments without supervision.

Experience with one or more high-throughput analysis pipelines for genomics, transcriptomics and/or proteomics etc. Proficiency in Unix (Linux) system, scripting (one, preferably two, of the following programming languages: Perl, Python, R, Java, and C/C++). Ability to research and implement best practices for data analysis for complex experiments.

Must have attention to detail, strong organizational skills, troubleshooting abilities and strong written and oral communication skills. Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude. Authorization to work in the United States without restriction.

Benefits

PPO/HMO Health Plan (includes medical, dental, and vision) 401K Retirement Plan Paid Time Off (PTO)