Postdoctoral Fellow, Laboratory of Dr. Dannie Engle

The Engle Lab focuses on understanding the etiology and progression of pancreatitis and pancreatic cancer to develop better prevention, diagnostic, and treatment strategies. Our research uses patient-derived organoids, molecular profiling, functional precision medicine, and in vivo models. Recent work established a comprehensive biobank of chronic pancreatitis patient-derived organoids and identified widespread CFTR dysfunction, including in patients without pathogenic CFTR mutations, revealing new opportunities to investigate targeted therapies for pancreatic disease.