Immunome

Senior / Principal Clinical Scientist, Clinical Development

Immunome

Bothell, Washington, United States$170k – $201kPosted Jul 20, 2026
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Job description

** Company Overview **

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been submitted to the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-3050, an IND-cleared FAP-targeted radiotherapy; and IM-1617, an IND-cleared solid tumor ADC. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.

** Position Overview **

We are seeking a highly motivated and experienced Clinical Scientist to join our team. The Senior / Principal Clinical Scientist, Clinical Development will play a critical role in the design, execution, and interpretation of multiple clinical trials for our oncology drug candidates. This individual will work closely with cross-functional teams, including clinical operations, regulatory affairs, and research and development, to ensure the successful progression of multiple clinical programs.

** Responsibilities **

  • Oversee the execution of clinical trials and ensure scientific and regulatory rigor.

  • Design and develop multiple clinical trial protocols, informed consent forms, and other study-related documents.

  • Collaborate with principal investigators, key opinion leaders, and clinical trial sites to ensure robust study design and execution. Serve as Lead Clinical Scientist for multiple trials.

  • Conduct activities related to data generation and validation, including CRF design and clinical data review/query resolution.

  • Contribute to the preparation of clinical study reports, regulatory submissions, and publications.

  • Review development of site and CRA training materials and presentation at SIV and Investigator meetings and support on Study committee (e.g., DMC) activities.

  • Perform site-facing activities such as training and responding to clinical questions.

  • Participate in the strategic development of clinical development plans and timelines.

  • Present clinical trial data and findings to internal and external stakeholders, including scientific advisory boards and regulatory agencies.

  • Mentor and develop junior team members with potential to manage direct reports.

** Qualifications **

  • PhD, MD, PharmD, MS, or equivalent degree in life sciences.

  • A minimum of 2 years of experience in clinical science, clinical research, or equivalent; clinical development experience is required, biopharmaceutical/biotechnology industry and oncology experience preferred.

  • Strong leadership, project management, and communication skills.

  • Travel may be required.

** Knowledge and Skills **

  • Extensive experience in drug development process, study design, clinical operations.

  • Extensive experience in clinical trial data analysis software and tools.

  • Strong knowledge and skills to support program specific data review, trend identification, and data interpretation.

  • Strong understanding of regulatory requirements and guidelines for clinical trials (e.g., GCP, ICH, FDA).

  • Excellent analytical, organizational, and communication skills.

  • Ability to work effectively in a fast-paced, collaborative environment.

  • Strong problem-solving skills and attention to detail.

WA State Range: Senior Clinical Scientist, Clinical Development - $ 145,823 - $182,019

WA State Range: Principal Clinical Scientist, Clinical Development - $ 169,883 - $200,742

Washington State Pay Range

$145,823 - $200,742 USD

** E/E/O **

Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

** E-Verify **

Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish) .