Piston Bio jobs and careers

About Piston Bio

Piston Bio is a clinical-stage biotechnology company developing therapies to overcome immune resistance in cancer. Our lead program, PST-101, is a best-in-class adenosine A2A receptor antagonist targeting a clinically validated immune checkpoint. We are advancing a randomized Phase 2 study in 2L+ non-small cell lung cancer, with progression-free survival as the primary endpoint. PST-101 is an oral, combination-ready therapy designed to integrate with standard of care and improve clinical outcomes. Piston Bio is focused on translating validated biology into meaningful survival benefit for patients with cancer.