Is Plume hiring right now?

Yes. Plume has 2 open roles listed as of October 29, 2026.

Where is Plume headquartered?

Plume is headquartered in Denver, Colorado, United States and was founded in 2019.

Matthew Wetschler, CEO and Co-founder, is at the top of Plume's org chart.

How do I apply for a job at Plume?

Pick a role on Plume's TheJobsMap page and select Apply. Every listing links to the original posting on Plume's own careers site, so you apply directly with the employer.

Plume jobs and careers

Denver, Colorado, United States. Jobs in Denver

As of October 29, 2026, Plume has 2 open roles.

getplume.co LinkedIn @plume_clinic

See 2 open roles

Headquartered in Denver

2Open roles

About Plume

Plume is a passion-fueled, mission-driven company that is trans-founded with a vision to transform healthcare for every trans life. We hope to make gender-affirming hormone therapy easily accessible at the touch of a button in every state of the US. This work is deeply personal and heart-driven, and we want teammates who care about the mission and the people we serve. For the right candidates, we present a rare opportunity to do well by doing good.

Founded in 2019 by Jerrica Kirkley, Matthew Wetschler and Shayta Roy Saha.

Health Care LGBT Lifestyle Medical

Founded: 2019
Employees: 51 to 100
Total funding: $38M
Headquarters: Denver

Leadership

The top of Plume's org chart, with how many people report into each leader.

Matthew Wetschler

CEO and Co-founder

53 reports

Jerrica Kirkley

Co-Founder & Chief Medical Officer

21 reports

Jess Frisen

Chief Operating Officer

14 reports

Nick Nieslanik

Svp, Product & Technology

12 reports

Sara Baier (Phr

Senior Director of People & Culture / Head of Human Resources

1 report

Dee S.

Sr. Director Of Communications

Open roles at Plume 2

Plume jobs: common questions

Is Plume hiring right now?: Yes. Plume has 2 open roles listed as of October 29, 2026.
Where is Plume headquartered?: Plume is headquartered in Denver, Colorado, United States and was founded in 2019.
Who leads Plume?: Matthew Wetschler, CEO and Co-founder, is at the top of Plume's org chart.
How do I apply for a job at Plume?: Pick a role on Plume's TheJobsMap page and select Apply. Every listing links to the original posting on Plume's own careers site, so you apply directly with the employer.