Postdoc

Job advertisement no. 754 The department BIIM, led by Prof. Yang Li , at the Centre for Individualised Infection Medicine (CiiM), is offering the position of a Postdoc (f/m/d) in Computational biology or bioinformatics. The CiiM was founded 2015 as a joint venture of the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH) and is the first research institute explicitly dedicated to develop personalized medicine for infections.

The departments and groups of the CiiM are working towards the vision of treating infectious patients in an adapted and optimized way according to the specific needs and requirements of each individual. To achieve this, CiiM is dedicated to researching individual characteristics and their impact on susceptibility to infection or treatment success with available therapies.

The department “Computational Biology for Individualised Medicine” studies the interaction of genetic background and environment and its contribution to infection and immune-related diseases. It focuses on applying and developing computational and statistical approaches to study the effect of genetic factors on a variety of molecular levels (such as genetics, genomics, metabolomics etc.)

, immunological parameters and functions, as well as on complex diseases to shape interindividual variations during infection and immune-related diseases. Infections and their sequelae continue to account for one in five deaths worldwide. In this context, emerging and recurrent pathogens, chronic infections, and increasing resistance to approved drugs continue to pose new challenges to physicians.

A central objective of the postdoctoral position is to identify actionable targets and biomarkers that can support risk stratification and guide interventions to maintain or restore immune competence in vulnerable populations. The work of the postdoctoral research associate will combine multi-omics data integration, high-dimensional immune phenotyping, and single-cell profiling to characterize immune states and connect them with clinically relevant infection and vaccination outcomes.

Responsibilities

Analysis and integration of multi-omics and single-cell omics data in the various cohorts Interpreting results with collaborators Take a leading role in writing and revising manuscripts Supervision of BSc/ MSc students, and/or PhD candidates Present data at local, national and international scientific meetings Requirements: Completed Degree/Diploma an PHD in bioinformatics/computational biology/statistics/computer science, or a related field of the life sciences A scientific publication record Skills in computer programming (e.

g. R, JAVA, Perl), experience with different operating systems (Linux, Windows) Very good communication and reporting skills Very good English communication skills (written and spoken) Ability to work independently and as part of an international team Experience in supervising students and PhD candidates Advantageous for this position: Engagement and commitment to succeed in science, be result-oriented Critical scientific attitude Molecular biology wet lab experience We offer you: An attractive and varied job in a future-oriented research institute A state-of-the-art infrastructure and the latest technologies Flexible working hours, part-time models as well as home office A corporate culture of appreciation and promotion of equal opportunities Extensive training and continuing education opportunities to develop professional knowledge and personal skills A family office to support family and career as well as childcare offers Interesting additional public service benefits Possibility of an employer subsidy for the job ticket People with severe disabilities and equivalent professional qualifications who are suitable for the position are given preference.

In order to protect your rights, we ask you to provide us with a clearly recognizable reference to the existence of a degree of severe disability in your cover letter or resume. The position is held at the Helmholtz Centre for Infection Research GmbH (HZI) in Braunschweig. The place of employment is Hannover. The HZI is actively committed to equality, diversity and integration.

For this reason, the HZI pursues the goal of professional equality between women and men. The position is suitable for part-time work. Starting date: As soon as possible. The contract will initially run for 2 years. Salary: E 13 TV EntGO Bund Working time: 39.00 hours per week Place of work: Hannover Probation period: 6 months Closing date: 05/11/2026 For further information please contact Prof.

Yang Li , phone 0511 22002 720 , email: yang.li@helmholtz-hzi.de . Link: https://www.helmholtz-hzi.de/en/research/research-groups/details/computational-biology-for-individualised-medicine/ Please apply via our career portal. Please include a cover letter, resume, (employment) references, certificates, and (if available) work samples or reference projects with your application materials.

Please refrain from sending a photo. We look forward to receiving your application!