Postdoctoral Fellow (Grifoni Lab)

The Grifoni lab is seeking a postdoctoral researcher to join projects related to immune responses to infection and vaccines. Dr. Grifoni's lab focuses on human and mouse T cell responses to infectious diseases, particularly Coronaviruses, Enteroviruses, Orthomyxoviruses, Orthopoxviruses, Arenaviruses, and other emergent viral pathogens relevant to worldwide global health.

The Grifoni lab work unravels T cell responses induced by infections and current or novel viral-based vaccines.

About the role

The ideal candidate would have an interest in translational research with applications in health care and will play a crucial role within a dedicated team of scientists and thrive in a supportive atmosphere that offers mentorship, nurtures talent, and promotes personal development and education. LJI is a globally recognized institution that offers outstanding perks and strong backing for its researchers.

List of relevant publications related to this position: Tarke et al., Cell Rep Med 2023; PMID: 37295422 Neto et al., Cell 2025; PMID: 40774254 Lee et al., Cell Rep Med 2026; PMID: 42161271 Snyder et al., Clin Immunol 2026; PMID: 41077293 Include in your application in one single file:

1. A cover letter describing your background and interest in the position
2. Your CV
3. Contact information for three references Required Qualifications: PhD or equivalent doctoral degree in immunology, virology, or bioinformatics Minimum 4 years of hands-on experience in T cell immunology and/or virology during their training. Proven track record of independent experimental design, optimization, and execution of cell culture, multi-color flow cytometry (10+ required, 20+ preferred), and Fluoro. Spot/ELISPOT assays. Excellent written and verbal communication skills, with a demonstrated ability to write scientific manuscripts.

Preferred Qualifications

Prior experience with in vivo mouse models of viral infection Experience analyzing large-scale datasets (e.g., viral sequences, scRNAseq, TCRseq), including proficiency with computational methods and relevant statistical software.

Benefits

Salary commensurate with experience Opportunities for professional development and advancement Access to cutting-edge facilities and resources for research Supportive and inclusive work environment fostering growth and innovation Networking opportunities with professionals in the field of immunology The La Jolla Institute for Immunology (LJI) offers a collegial work environment that emphasizes collaboration, teamwork and creativity.

Full-time employment at LJI includes a competitive salary, medical/dental/vision benefits, paid sick leave, and contributions to a retirement plan (403B). For the last decade, LJI has been ranked as one of the best places to work in San Diego by the San Diego Business Journal. The Institute hosts world-renowned faculty and over 80 postdoctoral researchers with scientists from over 30 countries.

LJI is located in the Science Research Park on the campus of UC San Diego, providing easy access to the San Diego life sciences community and all that the area has to offer. LJI provides Equal Employment Opportunity (EEO) to all employees and applicants for employment, and prohibits discrimination and harassment of any type, regardless of race, color, religion, age, sex, national origin, marital status, disability status, genetics, medical conditions, protected veteran status, sexual orientation, gender identity or expression, reproductive health decisions, or pregnancy, or any other condition protected by state and local laws.

This applies to all terms and conditions of employment, including recruitment, hiring, placing, training, promotion, compensation, benefits, transfers, educational assistance, terminations, layoffs, recalls, transfers, leaves of absences, and social and recreational programs. La Jolla Institute is committed to compensation that is externally competitive and internally equitable.

We validate this commitment by conducting regular market analyses to remain competitive with organizations of similar size in the nonprofit, independent research sector.

Compensation

decisions consider a variety of factors including experience, education, unique skill sets, organizational need, and internal equity.