Senior Scientist

NO AGENCIES

• PLEASE!

POSITION SUMMARY

We are seeking a highly motivated Senior Scientist, Proteomics to join our Translational Research team and play a central role in advancing a novel therapeutic asset across rare mitochondrial disorders, neurological diseases, oncology, and other indications. This individual will be a key driver of mechanism-of-action (MoA) studies, biomarker discovery/validation, enabling data-driven decision-making across preclinical and clinical development.

ESSENTIAL DUTIES AND RESPONSIBILITIES

Design and execute discovery and targeted proteomics experiments to support MoA, pharmacodynamics, and biomarker identification. Lead analysis of complex biological samples (plasma, tissue, CSF, cellular systems) using LC-MS/MS–based proteomics platforms. Drive biomarker discovery and validation, translating proteomic findings into clinically relevant biomarker candidates.

Collaborate closely with biology, pharmacology, bioinformatics, and clinical teams to support translational research strategy. Interpret and present results to cross-functional teams, and external collaborators. Contribute to regulatory and publication-quality documentation, including study reports and manuscripts. Stay current with advances in proteomics technologies, computational tools, and analytical methods to continuously improve platform capabilities.

Other duties, as assigned.

QUALIFICATIONS

Ph.D. in Proteomics, Biochemistry, Molecular Biology, Analytical Chemistry, or a related field. 4+ years of industry experience in proteomics or translational biomarker research (biotech or pharmaceutical environment preferred). Strong hands-on expertise in mass spectrometry–based proteomics Ability to work with an interdisciplinary team of biologists, chemists, and computational scientists to deeply characterize and understand the proteomes of cells, biofluids, and tissues.

Demonstrated ability to analyze, interpret and present data in a clear fashion. Experience integrating proteomics with multi-omics datasets and systems biology approaches is desired Solid scientific training/productivity as identified through high-impact publications demonstrating creative thinking as well as innovative technical approaches.