Postdoctoral Fellow-MSH-32076-171

Salary: According to UAW/Mount Sinai agreement, effective 7/1/25 starting salary $74,692 Department: 866 – Department of Immunology and Immunotherapy Location: 1470 Madison Ave., 5 th Floor, New York, NY 10029 Department website: https://icahn.mssm.edu/about/departments-offices/immunology-immunotherapy Laboratory website: https://labs.

icahn.mssm.edu/meradlab/ https://www.pulestonlab.com/ The Merad and Puleston Laboratories is seeking highly motivated postdocs to lead projects related to targeting age driven myeloid dysfunction in cancer: unraveling the immunomodulatory and metabolic contributions of GLP1 agonist Goals/Outcome of the research project: This project explores the immune effects of GLP1 receptor agonists (semaglutide and tirzepatide) in aging and disease.

Our findings show that GLP1 treatment reduces inflammaging and rescues age-related loss of resident alveolar macrophages with the goal of applying these findings to patients. Using state of the art in vivo stable isotope tracing technology, the incoming candidate will also explore how incretins modulate immune cell metabolism.

Technical Duties: (include any protocols) Perform independent research in mouse model, flow cytometry, scRNA-seq, scATAC-seq technology, confocal microscopy, cell culture and metabolism assays. Critically analyze data quality and results, communicate results to scientists and lay people Write or assist in writing scientific papers and grants Collaborate closely with other scientists to conduct research Qualifications: Ph.

D. required Experience working in a research laboratory setting This position is covered by a collective bargaining agreement between the ISMMS and the Sinai Postdoctoral Organizing Committee

• UAW. Wages and benefits: See Article 5 and 13 of The collective bargaining agreement found online at https://sinaipostdocunion.org/wp-content/uploads/2023/12/12-17-23-SPOC-UAW-_-Mount-Sinai-Tentative-Agreement-FINAL-PDF.pdf . Our mission at Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the many diverse communities we serve. Mount Sinai Health System is committed to diversity and equal opportunity Compensation Statement The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $74,692.00 - $80,000.00 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits. SPOC-UAW Local 4100 at Icahn School of Medicine (Post Docs), 866
• Immunology and Immunotherapy
• ISM, Icahn School of Medicine