Head of Engineering

Head of Engineering Compensation: $125K– $200K salary, up to 1.0% equity stock options Full benefits, including health coverage, PTO & parental leave About Biome. Sense Biome. Sense is a life sciences startup applying gut microbiome technologies (Gut. Lab, Meta. Biome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by Lab.

Corp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners.

Role Summary

Own the full hardware (HW) lifecycle for Gut. Lab, from architecture & subsystem integration through manufacturing, validation & deployment for a complex electromechanical device & BOM. Act as final technical authority for Gut. Lab system performance, fleet stability & next generation Gut. Labs (Gen3) production, combining hands-on engineering depth with strategic judgment to ensure current systems perform reliably in the field & Gen3 scales into manufacturing.

Key Responsibilities

System Ownership & Development : Own Gut. Lab architecture (electromechanical & fluidic); lead design, testing & refinement via CAD, prototyping & manufacturing Validation & Deployment Readiness: Own validation, stage gates, documentation & traceability across revisions, firmware & field performance. Lead troubleshooting, diagnostics & closed-loop fixes to eliminate systemic failure modes End-to-End Execution : Set & execute high standards for all aspects of HW development: procurement, transfer, sustaining engineering & operations Manufacturing Scale-Up : Drive DFM, design freeze, pilot builds, supplier alignment, cost targets & manufacturing strategy + execution for Gen3 Team Leadership : Mentor & lead a HW team; align resources, timelines & execution to production milestones Strategic Problem Solving : Address any and all procurement challenges while identifying cost-effective solutions Cross-Functional Collaboration : Partner with other leaders to align hardware development with broader company strategy & goals Qualifications 8+ years’ experience in hardware engineering for complex electromechanical systems Deep proficiency in CAD, tolerances, prototyping & manufacturing Product lifecycle ownership (concept through transfer & scale-up) Proven ability to build & manage technical teams Systems-level troubleshooting expertise across mechanical, fluidic & electronic Structured, decisive & execution-oriented with high accountability A strategic thinker who thrives under pressure in fast-paced environments Hiring Process Note: We are a small team and we review all resumes, screening questions and assessment scores manually.

However this focus on manual review limits our ability to respond to direct messages through LinkedIn and other channels. We appreciate your effort in applying and we thank you for your understanding.